A Novel High-Throughput Screening Assay for State-Dependent and Subunit-Dependent BK Channel Modulators
نویسندگان
چکیده
منابع مشابه
High-throughput screening for ion channel modulators.
Ion channels present a group of targets for major clinical indications, which have been difficult to address due to the lack of suitable rapid but biologically significant methodologies. To address the need for increased throughput in primary screening, the authors have set up a Beckman/Sagian core system to fully automate functional fluorescence-based assays that measure ion channel function. ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2019
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2018.11.1355